combination effect is higher than expected) or antagonistic (i.e. dose-response matrix or tensor, see figure above) are usually compared with expected combination responses calculated by means of synergy scoring models (so-called reference or null models).Ĭonsequently, based on deviation of observed and expected responses one can classify the drug combination either as synergistic (i.e. To evaluate the potential synergy of combined drugs, the observed drug combination responses (e.g. SynergyFinder is a stand-alone web-application for interactive analysis and visualization of multi-drug (2 or more drugs) multi-dose combination response data. ![]() Getting Started Welcome What is SynergyFinder?
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